What is Mesothelioma?

Mesothelioma (mez-uh-thee-lee-O-muh) is a type of cancer that begins in the tissue that line different organs and spaces inside the body. This tissue, called mesothelium (mez-uh-thee-le-um), protects organs by making a special fluid that allows the organs to move. For example, this fluid makes it easier for the lungs to move during breathing.

Mesothelium surrounds the lungs, the stomach, the heart, and other organs. Tumors can start in any of these places. These tumors can be benign or they can be cancerous. The information that follows covers only those that are cancerous.

There are three main types of mesotheliomas. The most common (50%-70%) is the epithelioid type. This type has the best outlook. The other two types are less common. The treatment choices for all three are the same.

About three out of four mesotheliomas start in the chest cavity. These are called pleural mesotheliomas. Another 10%-20% begin in the abdomen (peritoneal mesotheliomas). Those starting around the heart are very rare. This cancer can also start in the tissue around the testicles, but this is also very rare.

There are also benign (not cancer) tumors that can start in the mesothelium, but the information here applies only to malignant (cancerous) mesotheliomas.

What is Mesothelioma? Mesothelioma from the (Greek meso+ thelioma, tumor of middle lining tissue) is an uncommon cancer, originating from the cells which form the membrane lining the abdominal cavity (peritoneal membrane or peritoneum) which houses the intestines, or the chest (pleural membrane or pleura) cavity housing the heart and lungs, in which the cells making up those tissues begin to grow out of control.

Mesotheliomas most often are seen in older patients, more often men that have a history of occupational exposure to asbestos, although other causes such as radiation and certain viruses have occasionally been implicated. In a proportion of cases, no asbestos exposure...

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Mesothelioma is an incurable asbestos cancer. This short film was produced to raise awareness of the issues around mesothelioma. It includes ...

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When asbestos fibers get inside the body, they trigger a number of biological pathways that can eventually lead to the development of mesothelioma and other

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An Inviting but Challenging Target for Gene Therapy
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The retinoblastoma gene family pRb/p105, p107, pRb2/p130 and simian virus-40 large T-antigen in human mesotheliomas. Nat Med 1997;3:913–916.


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Malignant pleural mesothelioma is a rare disease known to be resistant to conventional therapies. A better understanding of mesothelioma biology may provide


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Mesotheliomas have been observed in people who were occupationally exposed to chrysotile, family members of the occupationally exposed, and residents who

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Mesotheliomas form a spectrum of tumors that usually arise in the ... The classic histopathology of the mesothelioma is a biphasic tumor with both an ...

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ACS :: What Is Malignant Mesothelioma?
A layer of specialized cells called mesothelial cells lines the chest cavity, abdominal cavity, and the cavity around your heart.



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